American Academy of Pediatrics Publishing Staff Mary Lou White, Chief Product and Services Officer/SVP, Membership, Marketing, and Publishing Mark Grimes, Vice President, Publishing Chris Wiberg, Senior Editor, Professional/Clinical Publishing Theresa Wiener, Production Manager, Clinical and Professional Publications Jennifer Shaw, Senior Medical Copy Editor Linda Diamond, Manager, Art Direction and Production Linda Smessaert, MSIMC, Senior Marketing Manager, Professional Resources Published by the American Academy of Pediatrics 345 Park Blvd Itasca, IL 60143 Telephone: 630/626-6000 Facsimile: 847/434-8000 The American Academy of Pediatrics is an organization of 67,000 primary care pediatricians, pediatric medical subspecialists, and pediatric surgical specialists dedicated to the health, safety, and well-being of infants, children, adolescents, and young adults. The recommendations in this publication do not indicate an exclusive course of treatment or serve as a standard of care. Variations, taking into account individual circumstances, may be appropriate. Statements and opinions expressed are those of the authors and not necessarily those of the American Academy of Pediatrics. Listing of resources does not imply an endorsement by the American Academy of Pediatrics (AAP). The AAP is not responsible for the content of external resources. Information was current at the time of publication. Brand names are furnished for identification purposes only. No endorsement of the manufacturers or products mentioned is implied. The publishers have made every effort to trace the copyright holders for borrowed material. If they have inadvertently overlooked any, they will be pleased to make the necessary arrangements at the first opportunity. This publication has been developed by the American Academy of Pediatrics. The authors, editors, and contributors are expert authorities in the field of pediatrics. No commercial involvement of any kind has been solicited or accepted in the development of the content of this publication. Every effort is made to keep Red Book Pediatric Infectious Diseases Clinical Decision Support Chart consistent with the most recent advice and information available from the American Academy of Pediatrics. Special discounts are available for bulk purchases of this publication. E-mail Special Sales at for more information. © 2019 American Academy of Pediatrics All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means—electronic, mechanical, photocopying, recording, or otherwise—without prior written permission from the publisher (locate title at and click on © Get permissions you may also fax the permissions editor at 847/434-8780 or e-mail Printed in the United States of America 9-415/2018 1 2 3 4 5 6 7 8 9 10 MA0914 ISBN: 978-1-61002-305-4 eBook: 978-1-61002-306-1 Contents Staphylococcal Infections 1 Streptococcal Infections 3 Diarrheal Infections 5 Immunizations (runs for 2 spreads) 7 Antibiotic Prophylaxis 11 Immune Globulin (runs for 2 spreads) 13 Kawasaki Disease 17 Tuberculosis 19 Lyme Disease 21 Varicella-Zoster 23 Zika 25 Fungal Infections 27 Genital and Neonatal Herpes 29 Syphilis 31 Immunocompromised Children and Adolescents 33 Introduction With each new edition, the recommendations in the American Academy of Pediatrics (AAP) Red Book are refined and enhanced to enable physicians to provide the best possible care to children presenting with infectious diseases. The comprehensive text is notably supplemented by a growing assortment of tables, algorithms, charts, and graphs, many of which have become popular features among the readership. Physicians have even been known to make photocopies of their favorite items to post on their office walls or desktops for easy reference. This speaks to an important need: Visual resources can be crucial at the point of care, and the format of a 1,200-page, 6" x 9" paperback book does not always do great favors for their accessibility. To make these resources more accessible and user-friendly at the point of care, I am pleased to introduce the Red Book Pediatric Infectious Diseases Clinical Decision Support Chart. This brand-new resource collects many of the most clinically useful tables, algorithms, and other items from the latest edition of the Red Book and presents them in an enlarged, enhanced, colorized format that is lightweight, portable, and easy to navigate. Each item has been thoughtfully re-rendered to take best advantage of the larger format and more dynamic visual palette. Additionally, several new tables have been created exclusively for this chart, synthesizing important clinical information from throughout the Red Book text. The content featured in these 15 information-rich tabs is derived directly from the 2018 Red Book, and has been reviewed by the Red Book editors to ensure consistency with AAP policy. Because this is a new product, we are interested in hearing how it is used by physicians in practice. We encourage you to let us know which items you find most helpful day to day, which could be further refined, and which topics you wish would be covered in future editions. This clinical decision support chart has been created with daily practice at top of mind with your help, we look forward to creating a resource that is truly responsive to the needs of physicians. David W. Kimberlin, MD, FAAP Editor, Red Book RBFC INTERIOR - 2018.indd 1 10/10/18 1:49 PM
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