Guide to Contraindications and Precautions to Immunizations, 2018 Vaccine Contraindications Precautionsa Conditions in Which Vaccines Should Be Given if Indicated General for all routinely administered vaccines (eg, DTaP, DT, Td, Tdap, IPV, MMR, MMRV, Hib, pneu- mococcal, meningococ- cal, hepatitis B, varicella, hepatitis A, influenza, zoster, rota- virus, HPV) Severe allergic reaction (eg, anaphylaxis) to a vaccine contraindicates further doses of that vaccine Severe allergic reaction (eg, anaphylaxis) to a vaccine constituent contraindicates the use of vaccines containing that substance Current moderate or severe illnesses with or without fever Latex allergyb Mild to moderate local reaction (soreness, redness, swelling) after a dose of an inject- able antigen Low-grade or moderate fever after a previ- ous vaccine dose Current mild acute illness with or without low-grade fever Current antimicrobial therapy Convalescent phase of illnesses Preterm birth (same dosage and indications as for healthy, full-term infants) hepatitis B is the exceptionc (see Hepatitis B, p 401) Recent exposure to an infectious disease History of penicillin or other nonspecific allergies or fact that relatives have such al- lergies Pregnancy of mother or household contact Unimmunized household contact Immunodeficient household contact Breastfeeding (nursing infant OR lactating mother) Lack of a physical examination 1072 APPENDIX V GUIDE TO CONTRAINDIC ATIONS
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